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Cahokia, Illinois
If the St. Louis area doesn’t sound like the most ancient of locales, think twice. Just across the Mississippi in Illinois stands the largest pre-Columbian settlement north of Mexico, Cahokia Mounds. Spread out across 2,200 acres, the landmark includes a prehistoric “earthwork” that towers nearly 100 feet high and once held a population upwards of 20,000. Keep your eye out for the reconstructed “Woodhenge,” a circle of wooden posts once used to track the stars.